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The analysis of the transcriptome of
2018-10-24
The analysis of the transcriptome of OXM-treated HSPCs was revealing. First, the data showed very clearly that the mRNA levels of mTERT were not different between treated and untreated animals. In vitro studies by others have shown that OXM can enhance telomerase activity through estrogen receptor-m
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In this study we dissected the role of RA signaling
2018-10-24
In this study, we dissected the role of RA signaling in human hematopoietic development, using a human pluripotent stem cell differentiation system as an in vitro model, to generate hematopoietic progenitors. We have identified multiple stages in development that are influenced by RA signaling, wher
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pkc inhibitor br Experimental Procedures br Acknowledgments
2018-10-24
Experimental Procedures Acknowledgments Introduction Spermatogonial stem pkc inhibitor (SSCs) give rise to the spermatogenesis that endures throughout the life of male animals (de Rooij and Russell, 2000; Meistrich and van Beek, 1993). SSCs reside in a special microenvironment termed a nich
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br Results br Discussion The experiments presented here
2018-10-24
Results Discussion The experiments presented here identify compounds that promote SKP self-renewal and proliferation in culture, and provide evidence that these compounds activate dermal precursors in vivo to promote skin repair. They also define the MEK-ERK pathway as a key self-renewal path
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Here we demonstrate that postnatal pituitary SOX
2018-10-24
Here we demonstrate that postnatal pituitary SOX2+ stem prostaglandin receptor are derived from the embryonic RP and that the Notch signaling pathway is essential for their proliferation, maintenance, and postnatal pituitary expansion. Furthermore, we present evidence that SOX2+ stem cells make a si
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cyproheptadine hcl Cardiac MRI was performed to assess poten
2018-10-24
Cardiac MRI was performed to assess potential changes in cardiac function due to teratoma growth. For this, a subacute model with cell delivery 4 days after ischemia reperfusion injury was chosen since functional improvements following the transplantation of human ESC-CMs have been reported for this
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We further show that Zfp iNSCs lines
2018-10-24
We further show that Zfp521-iNSCs lines established from fetal, neonatal, and adult fibroblasts have the capacity to differentiate in vitro into the three main cell types: neurons, astrocytes and oligodendrocytes. This trilineage differentiation potential was also retained in three clonally derived
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br Results br Discussion Our studies demonstrate
2018-10-24
Results Discussion Our studies demonstrate that legumain inhibits late stages of ex vivo OB differentiation and the formation of mineralized ECM, suggesting that legumain regulates the ECM-hBMSC interaction that is required for the expression of the mature OB phenotype (Mathews et al., 2012).
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br Discussion Although animal models have provided valuable
2018-10-24
Discussion Although animal models have provided valuable mechanistic insights into the pathophysiology of ALS, there has been a lack of success in translating these findings to therapies (Gladman et al., 2012). This is perhaps due to species-specific differences between humans and rodents, or be
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br General scheme and electrode configuration In the
2018-10-24
General scheme and electrode configuration In the new Soffron60 analyzer, axial (parallel to the guiding magnetic field) component of Bisindolylmaleimide V Supplier energy is measured with electric cut-off method characterized by high resolution and reliability and allowing data cross-checking.
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Consequently the motion of electrons in
2018-10-24
Consequently, the motion of electrons in the first stage is the free scattering of accelerated electrons in the coronal part of the magnetic field in the low-density plasma. The accelerated electrons may be subsequently captured into a magnetic trap and ‘leave’ to the loss cone according to the pitc
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The growth or the attenuation of the external load
2018-10-24
The growth or the attenuation of the external load increases the augend in Eq. (1) and transmits the ordered motion to twinning dislocations in the twinning plane and in the twinning direction. The interaction of a twin with stoppers in metals slows down its growth and contributes a component influ
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Y-27632 Introduction This point is well illustrated by the
2018-10-24
Introduction This point is well illustrated by the results obtained in the experimental study of free convection in a non-rotating cylinder [1], according to which varying the ratio of the physical parameters of the fluid and solid media has a significant impact on the flow structure and on the hea
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While one s own unemployment
2018-10-24
While one\'s own unemployment is a shock that seems to influence health and health behaviors, a partner\'s unemployment may also be stressful or bring about a buy Clozapine N-oxide in resources (Mendolia, 2014, Westman, Elzion, & Horoutz, 2004), thus influencing one\'s own health and well-being. Res
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Introduction The rapid economic growth that
2018-10-23
Introduction The rapid economic growth that emerging and developing economies experienced in the last decades, specially in the run-up to the global financial crisis of 2008–2009, gave a new life to the debate about economic convergence – i.e., whether poorer countries tend to grow faster than the
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