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br Conclusion br Introduction Ectodermal dysplasia ED
2018-11-15
Conclusion Introduction Ectodermal dysplasia (ED) comprises a large heterogeneous group of inherited disorders that are characterized by primary defects during the development of two or more glucose transport proteins that are derived from embryonic ectoderm. The tissues primarily involved ar
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br Discussion of the findings This study aimed at
2018-11-15
Discussion of the findings This study aimed at determining the relationship between constraints management and capacity utilization of tea processing firms in Kenya. This study focused on the constraints management and further tested whether constraints management could lead to improved capacity
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With increasing usage of colistin as the
2018-11-15
With increasing usage of colistin as the last therapy for many refractory clinical infections, resistance to colistin is becoming more widespread. Taken together, the data clearly show that the principal mechanism of colistin resistance in the Col-R and Col-D clinical A. baumannii strains is the los
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In various cases the electroforming
2018-11-14
In various cases, the electroforming technique is used in conjunction with rapid prototyping methods to produce both parts and molds in creating ibotenic acid manufacturer injection (Chan et al., 2003, Hsu et al., 2008, Monzon et al., 2006, Rennieet al., 2001, Yang and Le, 1999). Applying electrofo
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According to the urban scale grade
2018-11-14
According to the urban scale grade in China, a large city is one with a 5z between 1 million and 5 million, and a megacity has a city population that exceeds 10 million. Nanjing, the capital city of Jiangsu province and the political, economic, and cultural center of the province, has a population
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There are different motivations for walking that require
2018-11-14
There are different motivations for walking that require different elements from the built environment. Behavioral scientists have identified two primary motivations for walking: recreation and transportation (Giles-Corti et al., 2005; Saelens and Handy, 2008). Walking for recreation refers to walki
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br Experimental Procedures br Author Contributions P A J des
2018-11-14
Experimental Procedures Author Contributions P.A.J. designed and performed majority of the experiments and data analyses. P.D.W. performed limiting dilution assays and facilitated R-SPONDIN1 rescue experiments. N.K. generated and analyzed human breast samples from specific reproductive phases,
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The results of the Western blot analysis reveal that
2018-11-14
The results of the Western blot analysis reveal that downregulated expression of the examined proteins is observed in all transgenic 5×FAD mice, but is more pronounced for 6-month-old mice (nos. 6 and 8), especially for STIM2. In 4-month-old transgenic 5×FAD mice, STIM2 expression (2 and 4) was down
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br Immune profile of food allergy Despite the fact that
2018-11-14
Immune profile of food allergy Despite the fact that IgE plays a central role in the pathogenesis of food allergy, measurement of food-specific IgE is not diagnostic in isolation. Quantification of food-specific IgE antibody levels in serum can identify patients in the pediatric population who ar
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Regions of linkage disequilibrium LD
2018-11-14
Regions of linkage disequilibrium (LD) were defined for the three loci tagged by SNPs reaching genome-wide significance. rs17599026, associated with urinary frequency, tags a 106kb region of LD (base position 137,657,783–137,763,798; Fig. 2A) containing part of KDM3B (including the promoter region
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Substantial epidemics and sporadic outbreaks of
2018-11-14
Substantial epidemics and sporadic outbreaks of hepatitis E occur in tropical and sub-tropical countries (e.g., in India, Uganda, Sudan, and Mexico), with up to tens of thousands affected (Dalton et al., 2013; Kamar et al., 2012). Approximately two billion people (one-third of the world population)
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A surprising finding in the RV
2018-11-14
A surprising finding in the RV144 immune correlates analysis was that monomeric anti-Env IgA in plasma may mitigate otherwise protective IgG responses (Haynes et al., 2012, Tomaras et al., 2013). Both IgA and IgG antibody isotypes are key mediators of defense against pathogen invasion. Although IgG
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Given the competing roles described above an
2018-11-14
Given the competing roles described above, an important question is whether treatment of cancer by autophagy inhibition will lead to neurodegenerative side effects and likewise, that treatment of neurodegenerative diseases with autophagy promoting agents might promote pre-malignant tumors. There are
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In a study published in
2018-11-14
In a study published in in February 2017, investigators from the Infant Brain Imaging Study (IBIS) described promising findings in screening children for autism spectrum disorders (ASDs). Using Tozadenant magnetic resonance imaging (MRI) to assess cortical development and brain volume, investigator
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terbinafine hydrochloride Characteristics of breast cancer p
2018-11-14
Characteristics of breast cancer patients and healthy controls together with crude ORs from univariable analyses are shown in Table 1. As expected positive family history of breast cancer was the most pronounced risk factor. Further characteristics that were significantly different between cases and
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