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It is well known that nanostructured transition metal oxides
2021-04-28
It is well known that, nanostructured transition metal oxides are the most promising candidates as electrode for pseudocapacitors due to their attractive properties such as environmentally friendly, high theoretical capacitance, low cost and easily abundant [15], [16]. Numerous investigations have b
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br Conclusions br Acknowledgements br Introduction Liver
2021-04-28
Conclusions Acknowledgements Introduction Liver cancer was the fifth most common cancer and the second leading cause of cancer-related death worldwide [1]. Most of primary liver cancers (70–90%) occurring worldwide are hepatocellular carcinoma (HCC) [2]. Persistent hepatitis B virus (HBV) i
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The protein levels of the three enzymes in the organs
2021-04-27
The protein levels of the three enzymes in the organs in the three earthworm species ranked body wall > intestine > seminal receptacle ≈ seminal vesicle (Fig. 3B).The presence of significant detoxification capability in the body wall would be logically expected in a soil dwelling organism, to facili
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These evidence prompted us to investigate the effectiveness
2021-04-27
These evidence prompted us to investigate the effectiveness of CT-133, a newly discovered, well-tolerated, selective and potent CRTH2 antagonist, as a treatment of ALI. CT-133 has shown a potential response in treating chronic obstructive pulmonary disease (COPD), allergic rhinitis and Phenformin au
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Growing evidence has shown that ANS
2021-04-27
Growing evidence has shown that ANS dysregulation, indexed by heart rate variability (HRV), plays a critical role in the pathogenesis of anxiety (Minassian et al., 2014, 2015). Indeed, we have previously reported that patients with GAD are associated with reduced resting parasympathetical (vagal) co
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58 4 mg Replacement of the saturated propoxy group in compou
2021-04-27
Replacement of the saturated -propoxy group in compound with the unsaturated allyloxy group to obtain compound resulted in 10-fold decrease in ET receptor antagonism and more than 20-fold decrease in ET-selectivity. Analogous unsaturated allyloxy compound in the tetrazole series was found to have
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br Results br Discussion Adaptive
2021-04-27
Results Discussion Adaptive drug resistance is a major challenge to the clinical success of cancer therapies. Incomplete inhibition of oncogenic signaling allows survival of “drug-tolerant” tumor cells, which persist in that state for variable periods before acquiring additional genetic mutati
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br Introduction Prostaglandins are important local mediators
2021-04-27
Introduction Prostaglandins are important local mediators in a host of reproductive processes including ovulation, fertilization, embryonic development, luteal regression, and parturition (Ushikubi et al., 2000). Prostaglandin E2 (PGE2) is among the more versatile prostanoids, and its effects app
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Several studies have indicated that ICT induces
2021-04-26
Several studies have indicated that ICT induces activation of ERK and p38 kinase in a variety of cells. The ERK pathway was involved in and partly contributed to the neuroprotective effects in rat neuronal vadadustat [14] and anticancer effects in several cancer cells [5], [7], [8]. ICT could also s
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br Materials and methods br Results br Discussion In general
2021-04-26
Materials and methods Results Discussion In general, CI symptoms are often visible only after the chilled products have been removed from coolstore to a warmer temperature (Schirra and Cohen, 1999). However, in the present work, 'satsuma’ mandarin fruit stored at 2°C showed chilling symptom
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histamine inhibitors br The role of chemokine and AD Chemoki
2021-04-26
The role of chemokine and AD Chemokines are small cytokine proteins that are involved in various immunological and physiological functions. These proteins can be involved in cell migration and localization during homeostasis and inflammation, and as such, they were named chemokines [80]. Chemokin
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Several single nucleotide polymorphisms SNPs in humans affec
2021-04-26
Several single nucleotide polymorphisms (SNPs) in humans affect CYP3A expression and activity (Lamba et al., 2002). The CYP3A4 SNP rs2740574 (also referred to as CYP3A4*1B, by The Human Cytochrome P450 (CYP) Allele Nomenclature Database, http://www.cypalleles.ki.se/) is a change in the promoter regi
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p kip is a member
2021-04-26
p27kip1 is a member of the cyclin-dependent kinase (CDK) inhibitor family that acts as a potent tumor suppressor in a variety of human cancers and negatively regulates the transition of cells from the G1 to S phase of the cell cycle, protects against inflammatory injury and promotes epithelial diffe
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Cryoprotectant equilibration and the response to
2021-04-26
Cryoprotectant equilibration and the response to ice concentrated media are the two facets of cellular cryobiological protocols most commonly covered by mathematical modeling. In these models, Estradiol Cypionate australia are typically assumed to have uniform, spatially independent extracellular c
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br Conclusions Enzyme can be delivered to the
2021-04-26
Conclusions Enzyme can be delivered to the tumour by using humanised or fully human npy receptor or even loaded into synthetic nanospheres produced from silica [64] or liposomally entrapped [65]. For any future ADEPT developments, a number of basic points need to be considered. As immunogenicity
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