• While PLGA implants could be beneficial

  2022-08-05

  

  While PLGA implants could be beneficial for regenerative angiogenesis in the context of wound healing, they Angiotensin Fragment 1-7 acetate could also lead to adverse effects. Indeed, extracellular acidification inhibits osteoblast proliferation, differentiation, and extracellular matrix mineraliza

• A linker length of and atoms was

  2022-08-05

  

  A linker length of 4 and 5 atoms was found to be optimal ( and ) compared to the only weakly active compounds with longer linkers ( and ) or the inactive compounds with shorter linker chains (–). In a next step incorporation of hetero-atoms in the linker was explored (). An amide linker as in and d

• To determine the functional consequences of HIV gp binding t

  2022-08-05

  

  To determine the functional consequences of HIV gp120 binding to vaginal epithelial cells, an annotation clustering of the differentially expressed genes was performed. The top enriched biological processes included an inflammatory immune response, defense response and the pathways included the SODD

• The existence of EAAT subtypes raises obvious questions as t

  2022-08-05

  

  The existence of 5 EAAT subtypes raises obvious questions as to the cellular and anatomical distribution of the various transporters (for review, see Gegelashvili & Schousboe, 1998, Danbolt, 2001). While difference in techniques (i.e., protein vs. mRNA), reagents, and preparations (i.e., in vivo vs.

• It is an aspiring task to

  2022-08-05

  

  It is an aspiring task to apply the glutamate biosensor for in vivo measurements in PFK-015 australia tissue. Due to a relatively large size of the electrode used in this work, the biosensor fits only ex vivo applications. However, it is possible to apply platinum microelectrodes 50–100 μm in diame

• Na K ATPase adenosine triphosphate ATP and astrocytic glutam

  2022-08-05

  

  Na+/K+-ATPase, Griseofulvin receptor and astrocytic glutamate transporters act together to maintain sodium and potassium gradients and the proper activities of EAAT1 and EAAT2 (Rose et al., 2009; Sheean et al., 2013); nevertheless, in present study, Na+/K+-ATPase activity was shown to be increased

• br Results br Discussion ER and GR play opposite phenotypic

  2022-08-05

  

  Results Discussion ER and GR play opposite phenotypic roles in the normal endometrium, with ER promoting growth and GR inhibiting growth. Here, we show that in endometrial cancer, GR expression is associated with worse outcomes and higher-grade tumors, and this association is observed only in

• In accordance with its similarity to classical NLSs Importin

  2022-08-05

  

  In accordance with its similarity to classical NLSs, Importin α3 was recently reported as a nuclear transport receptor for Ci (). We therefore superimposed the Gli1 NLS model with the Importin α2 structure (3EFX), which has a structure similar to Drosophila Importin α3 () (Fig. 4.4B). Gli1 NLS fitte

• Introduction Glucose dependent insulinotropic polypeptide GI

  2022-08-05

  

  Introduction Glucose-dependent insulinotropic polypeptide (GIP) is a hormone secreted postprandially from enteroendocrine K cells in response to ingestion of either fat [1], protein [2], or carbohydrates [3]. GIP is primarily known for its glucose-dependent insulinotropic actions mediated via the G

• Galanin a amino acid peptide was

  2022-08-05

  

  Galanin, a 29/30-amino-acid peptide, was first isolated in 1983 from porcine intestine by Tatemoto and collaborators [70]. It is widely distributed throughout the central and peripheral nervous systems as well as other tissues. It is involved in a wide range of physiological functions, such as modul

• br Short Communication Lactococcus lactis is traditionally u

  2022-08-05

  

  Short Communication Lactococcus lactis is traditionally used as a starter culture in the production of fermented dairy food products, such as cheese, sour cream, and buttermilk (Cavanagh et al., 2015). Two main pathways of lactose uptake and metabolism have been described for L. lactis. In the fi

• The ability of GPX and

  2022-08-04

  

  The ability of GPX4 and other selenoproteins to be selectively induced by ferroptotic stimuli suggests that the stress-induced increase in the transcription of a number of putative, “antioxidant” selenoproteins is an adaptive homeostatic, but insufficient response to prevent cell death in the face o

• Liver and muscle isozymes have been found in

  2022-08-04

  

  Liver and muscle isozymes have been found in vertebrate tissues [2], [5], [6]. The liver FBPase is recognized as a regulatory enzyme of gluconeogenesis. The muscle isozyme participates in the glycogen synthesis from lactate and in the regulation of glycolysis [7], [8], [9]. The basic difference betw

• br Conflict of interest br Introduction HAT is

  2022-08-04

  

  Conflict of interest Introduction HAT1 is the founding member of an expanding class of enzymes known as type B histone acetyltransferases (HATs). HATs are divided into two categories, type A and type B [1]. The type A HATs are nuclear enzymes that acetylate histones in the context of Arotinoid

• Relative to the impact of moderate

  2022-08-04

  

  Relative to the impact of moderate PAE on markers of histaminergic neurotransmission, there were four salient observations from the studies reported here. First, it does not appear that moderate PAE affects the number of HDC-positive neurons in the tuberomammillary nucleus of the ventral hypothalamu

16090 records 393/1073 page Previous Next First page 上5页 391392393394395 下5页 Last page