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Treating Age related Macular Degeneration Using Human iPS
2018-11-05
Treating Age-related Macular Degeneration Using Human iPS Cells Age-related macular degeneration (AMD) is a medical condition of the eye that results in blurred vision and/or a loss of central vision. The wet form of AMD – caused by abnormal blood vessel growth – is often treated using anti-VEGF me
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br Ethical approval br Introduction The
2018-11-05
Ethical approval Introduction The presence of metal ions in the environment is of major concern due to their toxicity to many life forms. Unlike organic pollutants, the majority of which are susceptible to biological degradation, metal ions do not degrade into harmless end-products. The metals
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Introduction The Sn and W mineral deposits in
2018-11-05
Introduction The Sn and W mineral deposits in southern China were historically suggested to have formed as part of one mineralizing event (Hsu, 1943), although the W ores are mainly distributed in the eastern part of southern China, whereas most Sn deposits are in the western part (Chen et al., 198
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Study inclusion for the current trial required
2018-11-05
Study inclusion for the current trial required self-reported unrefreshed or disturbed sleep. Although sleep disturbances are a hallmark feature of CFS [1], only a proportion of the participants had poor sleep over the baseline week of the study, as measured by actigraphy. There are a few possible ex
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br Material and methods br
2018-11-05
Material and methods Results and discussion Conclusions We developed a novel SERS-active optical fiber based on the design of 3D pore structure enriched with Ag nanoparticles. The in situ thermal-polymerized GMA-co-EDMA formed a quasi-spherical porous structure with the pore size of 0.29–0.
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El a o de la
2018-11-05
El año de la crisis, las exportaciones reaccionaron claramente ante la devaluación cambiaria y, junto con un entorno económico internacional positivo, las petroleras y las no petroleras se expandieron. Este aumento compensó, parcialmente, la caída del gasto interno. Pero ese año, el crecimiento econ
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These characteristics of Tat secretion are remarkably overla
2018-11-03
These characteristics of Tat secretion are remarkably overlapping with those of cellular FGF-2, which is also sensitive to ouabain and involves binding of the factor to the Na+,K+-ATPase (Dahl et al., 2000; Florkiewicz et al., 1998; Smith et al., 2001; Trudel et al., 2000; Zeitler et al., 2015), whi
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We found marked increases in GMVs
2018-11-03
We found marked increases in GMVs of the VS and mOFC. As a key region in the orbitofronto-striato-thalamic pathway (Menzies et al., 2008; Milad and Rauch, 2012; Pauls et al., 2014), VS (mainly the nucleus accumbens in this study) demonstrated significant enlargement as in previous studies (Norman et
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To gain insight into the biological significance of
2018-11-03
To gain insight into the biological significance of the changes observed, the proteins were grouped according to their annotated function and the Gene Ontology information [1]. The majority of the proteins with known functions were associated with photosynthesis, CO2 fixation and carbohydrate metabo
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br Experimental design materials and methods Kinetic Fitting
2018-11-03
Experimental design, materials and methods Kinetic Fitting: we used a fitting procedure that minimizes the error between the experimental data (concentration of the final double stranded complex as a function of time) and the solution of the model as obtained with an ordinary differential equatio
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Fig presents the EBSD micrographs obtained for the nanometri
2018-11-03
Fig. 3 presents the EBSD micrographs obtained for the nanometric powders. Analyzing these data revealed the lack of any preferential orientation. Relative densities were measured at 95.8% for the direct-SPS sample (a), and 93.9 for the CIP-SPS sample (b), with a relative density of the green sample
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br Data The datasets of this article provide additional
2018-11-03
Data The datasets of this article provide additional information to [1] and contains four categories of data (datasets). The first dataset contains the optimization input and output data used in the statistical analysis in section 4.1.4 of [1] to compare between two supplier ranking approaches in
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signaling Adolescence is a critical period of
2018-11-03
Adolescence is a critical period of neural maturation, during which there is reorganization of cortical connections, an increase in the fidelity of corticolimbic interactions, and neurochemical changes that promote adaptive behavioral regulation (). Gray matter develops along a nonlinear trajectory
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Findings from the present study lend
2018-11-03
Findings from the present study lend support to evidence from behavioral, cellular, and ERP research that when syntactic unification skills are not yet at the level necessary to effectively perform a grammaticality judgment task (as demonstrated by the lack of a P600 effect and beta power decreases)
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The brain should also be expected to
2018-11-03
The selective androgen receptor modulators should also be expected to underlie differential susceptibility inasmuch as it is intrinsically and reciprocally interconnected with genotypic to phenotypic systems already empirically demonstrated to manifest susceptibility. Activation of the anterior cin
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