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There are different motivations for walking that require
2018-11-14
There are different motivations for walking that require different elements from the built environment. Behavioral scientists have identified two primary motivations for walking: recreation and transportation (Giles-Corti et al., 2005; Saelens and Handy, 2008). Walking for recreation refers to walki
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br Experimental Procedures br Author Contributions P A J des
2018-11-14
Experimental Procedures Author Contributions P.A.J. designed and performed majority of the experiments and data analyses. P.D.W. performed limiting dilution assays and facilitated R-SPONDIN1 rescue experiments. N.K. generated and analyzed human breast samples from specific reproductive phases,
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The results of the Western blot analysis reveal that
2018-11-14
The results of the Western blot analysis reveal that downregulated expression of the examined proteins is observed in all transgenic 5×FAD mice, but is more pronounced for 6-month-old mice (nos. 6 and 8), especially for STIM2. In 4-month-old transgenic 5×FAD mice, STIM2 expression (2 and 4) was down
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br Immune profile of food allergy Despite the fact that
2018-11-14
Immune profile of food allergy Despite the fact that IgE plays a central role in the pathogenesis of food allergy, measurement of food-specific IgE is not diagnostic in isolation. Quantification of food-specific IgE antibody levels in serum can identify patients in the pediatric population who ar
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Regions of linkage disequilibrium LD
2018-11-14
Regions of linkage disequilibrium (LD) were defined for the three loci tagged by SNPs reaching genome-wide significance. rs17599026, associated with urinary frequency, tags a 106kb region of LD (base position 137,657,783–137,763,798; Fig. 2A) containing part of KDM3B (including the promoter region
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Substantial epidemics and sporadic outbreaks of
2018-11-14
Substantial epidemics and sporadic outbreaks of hepatitis E occur in tropical and sub-tropical countries (e.g., in India, Uganda, Sudan, and Mexico), with up to tens of thousands affected (Dalton et al., 2013; Kamar et al., 2012). Approximately two billion people (one-third of the world population)
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A surprising finding in the RV
2018-11-14
A surprising finding in the RV144 immune correlates analysis was that monomeric anti-Env IgA in plasma may mitigate otherwise protective IgG responses (Haynes et al., 2012, Tomaras et al., 2013). Both IgA and IgG antibody isotypes are key mediators of defense against pathogen invasion. Although IgG
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Given the competing roles described above an
2018-11-14
Given the competing roles described above, an important question is whether treatment of cancer by autophagy inhibition will lead to neurodegenerative side effects and likewise, that treatment of neurodegenerative diseases with autophagy promoting agents might promote pre-malignant tumors. There are
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In a study published in
2018-11-14
In a study published in in February 2017, investigators from the Infant Brain Imaging Study (IBIS) described promising findings in screening children for autism spectrum disorders (ASDs). Using Tozadenant magnetic resonance imaging (MRI) to assess cortical development and brain volume, investigator
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terbinafine hydrochloride Characteristics of breast cancer p
2018-11-14
Characteristics of breast cancer patients and healthy controls together with crude ORs from univariable analyses are shown in Table 1. As expected positive family history of breast cancer was the most pronounced risk factor. Further characteristics that were significantly different between cases and
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br Acknowledgment br Data This paper presents tables and
2018-11-14
Acknowledgment Data This paper presents tables and charts describing the variation in how minutiae are marked on latent fingerprints by latent print examiners, in support of the article “Interexaminer variation of minutia markup on latent fingerprints” [1]. The underlying data was collected in
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Fig demonstrates the modal intensity of
2018-11-14
Fig. 2 demonstrates the modal intensity of the proposed PCF for both of elliptical and circular holes in core region in X-polarization and Y-polarization mode respectively. We have compiled two proposed PCF based sensor using FEM based commercial tool COMSOL Multiphysics version 4.2. Furthermore, fi
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As was discussed in Ref Section there is a
2018-11-14
As was discussed in Ref. [2] (Section 4.1), there is a dependence of the slip length and coefficients on the flow channel thickness ; however the dependence is removed completely for the channel height larger than 100 times of fiber radius , where the universal slip behavior is observed independent
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br Results br Discussion br Conclusion The development of al
2018-11-14
Results Discussion Conclusion The development of alternative cement in developing countries is facing a triple challenge: a very fast increase in demand due to population as well as economic rise, low capital investment possibilities in an economic market with risky perspectives and a need
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Another limitation of this study can be seen in
2018-11-13
Another limitation of this study can be seen in the relative small number of participants; this was due to significant logistical challenges in recruiting and retaining the participants, especially these from low socio-economic backgrounds. Under the circumstances, and given that the three groups sh
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