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br In a detailed analysis using multiple data sources in
2019-04-17
In a detailed analysis using multiple data sources in this issue of , Emily Keats and colleagues show that Kenya made some progress in reducing maternal and newborn mortality between 2003 and 2015, and made greater progress in reducing child mortality between 1998 and 2015, after earlier increases
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When compared with lidocaine both amiodarone
2019-04-17
When compared with lidocaine, both amiodarone and nifekalant were proved similarly effective for ventricular arrhythmias suppression. These drugs, however, have characteristic adverse effects, such as negative inotropic and chronotropic outcomes (amiodarone), and QT prolongation resulting in torsade
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br Conflicts of interest br Acknowledgment This work was
2019-04-17
Conflicts of interest Acknowledgment This work was supported, in part, by a grant from the Experimental Research Center ELPEN (Y97/2-12-2013). The funding source had no involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the report, and in
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will be remembered as an exceptional year in shaping
2019-04-17
2013 will be remembered as an exceptional year in shaping our strategy to control HIV/AIDS. Indeed, a few weeks after the 30th anniversary of the discovery of the virus, a decisive step was made in deciding how to use antiretroviral therapy (ART) for treatment and prevention worldwide. New WHO publi
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br Raising taxes on tobacco is the measure with the
2019-04-17
Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2
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Desde aqu partiremos para apreciar
2019-04-17
Desde aquí partiremos para apreciar las virtudes de la perspectiva de Villoro en la defensa de la diversidad cultural frente a la postura de Garzón Valdés, Villoro señala que el problema de la diversidad cultural no está en la ponderación de la superioridad técnica de la cultura mayoritaria, sino en
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Bisphosphonates are a well established
2019-04-16
Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated
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To more accurately map the
2019-04-16
To more accurately map the del(7q) and to search for other submicroscopic aberrations, we performed BAC-based array CGH analysis on BM from the accelerated phase. This confirmed an interstitial deletion in chromosome bands 7q22.1-q35 of maximal size 50.0Mb (Fig. 2D). The minimal region of deletion e
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br A new model of human wellbeing is emerging
2019-04-16
A new model of human wellbeing is emerging to guide humanity in the Anthropocene. In essence, it recognises that wellbeing depends on enabling every person to lead a life of dignity and opportunity, while safeguarding the integrity of Earth\'s life-supporting systems. The conceptual framework of s
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There was a modest excess risk of
2019-04-16
There was a modest excess risk of mortality associated with multidrug-resistant organisms, which was lower than that previously recorded in south Asia. There are methodological challenges in the attribution of excess neonatal mortality with antimicrobial resistance because of known confounding with
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sglt-2 South Africa was the first African country to impleme
2019-04-16
South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age
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Etoposide One week after the CCRT she was brought to our
2019-04-16
One week after the CCRT, she was brought to our emergency department due to fever, severe general weakness, and severe oral pain. Her Sicca syndrome-related xerostomia had worsened due to radiotherapy and was complicated with severe stomatitis, which made oral intake difficult. She took traditional
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br Introduction Patients with advanced breast prostate lung
2019-04-16
Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly
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FD appears radiographically as radiolucent areas
2019-04-16
FD appears radiographically as radiolucent areas which later develop into a partially opaque ground glass appearance [51]. Other features that may be present are endosteal scalloping, bony expansion, and a thick reactive bone ‘rind’ [54]. MR imaging may be a more effective tool at identifying the si
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Por otro lado cabe subrayar que esta eleg a de
2019-04-16
Por otro lado, cabe subrayar que esta “elegía” de Pellicer se asemeja al género precolombino del icnocuicatl, los “Canto[s] de desolación, de orfandad” (Garibay 1992: 89). Según Garibay, estos cantos precolombinos “tienen parentesco con las elegías […] de los poetas de Occidente, en que se canta la
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