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A number of animal models of CLI including
2018-10-26
A number of animal models of CLI, including the hindlimb ischemia model after femoral artery ligation in rats (Rochester et al., 1994) and rabbits (Hao et al., 2014), have been proven useful to assess the effects of various cell types and to study potential mechanisms of action. For instance, IM inj
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For live cell imaging we established a well
2018-10-26
For live-cell imaging, we established a 96-well plate-based screening assay to assess expression of the pluripotency-associated surface marker TRA-1-60, a more reliable and specific marker for predicting successful reprogramming and iPS cell derivation than other markers including AP (Mali et al.,
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At a global level the analysis of DNA methylation
2018-10-26
At a global level, the analysis of DNA-methylation profiles provides important insights into molecular and cell growth characteristics of PSC that would otherwise be difficult to identify. Reprogramming-associated variations in X-linked CpG methylation is of particular interest because of the comple
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br Results br Discussion Hepatocyte like cells generated fro
2018-10-26
Results Discussion Hepatocyte-like cells generated from iPSCs can be used to model liver development and disease, for toxicity studies, and potentially could offer a source of hepatocytes for cell therapy (Rashid et al., 2010; Delaforest et al., 2011; Cayo et al., 2012; Fox et al., 2014). Whil
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progesterone receptor A number of differentiation protocols
2018-10-26
A number of differentiation protocols for the derivation of MSNs have been published (Arber et al., 2015; Delli Carri et al., 2013). In this study, using a modified version of the protocol of Delli Carri et al. (2013), we derived neurons from CAG180 hiPSCs capable of survival for over 3 weeks, the m
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br Discussion This cross national study examined
2018-10-26
Discussion This cross-national study examined self-reported perceptions of the importance of spiritual health in the lives of adolescent children in six countries. We explored patterns of children׳s perceptions of the importance of spiritual health, overall and by domain, related to developmental
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In the Middle East late diagnosis
2018-10-26
In the Middle East, late diagnosis has been attributed to the lack of knowledge about BC, and to the limited access to information on screening programs (Altwalbeh, El Dahshan, & Yassin, 2015; Lodhi, Ahmad, Shah, & Naeem, 2010). However, there is scant published literature from this region on the re
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br A life course perspective on
2018-10-26
A life-course perspective on legal status stratification and health We propose the life-course perspective (LCP) as a framework that offers a comprehensive theoretical lens for studying the health consequences of legal status stratification and for understanding legal status stratification as a s
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The crude odds ratio OR of
2018-10-26
The crude odds ratio (OR) of participation in the NSE class once a month at baseline against poor SRH two years later was 0.53 (95% CI: 0.34–0.85). The OR after adjusting for age and sex was 0.49 (95% CI: 0.30–0.78). Even after NSE class participation once a month at baseline against poor SRH two ye
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br Non human subject research br Acknowledgements The author
2018-10-26
Non-human subject research Acknowledgements The authors gratefully acknowledge use of the services and facilities of the Population Studies Center at the University of Michigan, funded by NICHD Center Grant R24 HD041028 and the support of an NICHD training grant to the Population Studies Cente
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We are particularly interested in how socioeconomic
2018-10-26
We are particularly interested in how socioeconomic status (SES) is associated with multimorbidity earlier in the lifecourse. Low SES has been linked to greater occurrence of numerous individual chronic conditions, including hypertension (Vargas, Ingram, & Gillum, 2000) heart disease (Thurston, Kubz
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Likewise members with social goals join the
2018-10-26
Likewise, members with social goals join the TB as they see in this alternative market an instrument to meet new people, extend their social network, be of help to their neighbors and, in short, nurture social capital by bonding and developing trust with one another (Collom, 2008; North, 2014). Ther
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In this paper solid state and sonochemical reaction methods
2018-10-26
In this paper, solid state and sonochemical reaction methods are used to produce the Mgdoped bulk and nano LSMMO (0.050 ≤ x ≤ 0.100) manganite perovskite, respectively. The structural as well as the magnetic properties of LSMMO manganite perovskites are revealed employing different characterisation
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Twin T an identical twin remained in hospital
2018-10-26
Twin 2 (T2), an identical twin, remained in hospital for 38 days after childbirth complications, but her further neurological, psychological and motor development was normal. She started migrane onset at 9 yo. At 14, she reported symptoms directly related to excess sleepiness interfering in her ever
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br Conflict of interest br Acknowledgment br Introduction Re
2018-10-26
Conflict of interest Acknowledgment Introduction Recently much effort has been spent in the area of microarrays to bring this technology into non-research markets [6,25]. One of the drivers for technology is the demand for point-of-care diagnostics (POC) [18]. Several attempts have been mad
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