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We also find that PRKCZ fails
2018-11-02
We also find that PRKCZ fails to accumulate normally at the apical membrane in Gata3 mutant embryos, even though its expression and activation levels are maintained. PRKCZ is part of the apical Par complex comprising PARD3 and PARD6B and acts as a key regulator of mitotic spindle orientation in othe
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br The configuration of the system for
2018-11-02
The configuration of the system for photochemical reaction imaging The system is placed in a compact case that is effectively an intraoral camera with a built-in emitter. The camera field of view at a working distance from the object (about 15 mm) is 1 cm2. The construction of the system provides
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The rapid development of radio astronomy began
2018-11-02
The rapid development of radio astronomy began in 1945. The first objects examined in the radio range were gas nebulae of large angular size, sufficiently bright in this range; there was no difficulty in identifying them with optical objects. However, it neuron specific enolase soon became clear th
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Many prior studies have investigated individual level
2018-11-02
Many prior studies have investigated individual-level predictors of 2009 A(H1N1) pandemic ldv acceptance. For example older age, higher education, belonging to an ethnic majority, belonging to a priority group, receiving recommendations from a health professional, receiving information from friends
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Analysts may empirically check if the
2018-11-02
Analysts may empirically check if the outcome variable has an ICC that V5 Epitope is distinguishable from zero, as introduced briefly above. Even those favoring a priori specification of how the model will account for clustering, coauthor or reviewer suggestions may warrant an empirically-informed r
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Average hours of sleep per day
2018-11-01
Average hours of sleep per day was 7.9±1.7h, consistent with the suggestion of the US National Sleep Foundation (between 7 and 9h) and what has been reported in Latin America in 1776 individuals from 18 to 70 years of age from three of the largest cities where an average of 5.8h of sleep per day was
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br Introduction The DNA chip microarray is widely used
2018-11-01
Introduction The DNA chip (microarray) is widely used in genotyping and gene expression analysis as a tool capable of detecting two or more genes simultaneously [2,16,19,20]. However, it is suitable for use only in research since the detection limit, dynamic range and detection time are insuffici
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To assess if these biomarkers could predict subsequent diagn
2018-11-01
To assess if these biomarkers could predict subsequent diagnosis of lung cancer, we performed association study between the variables and lung cancer. In multivariable logistic regression analyses among all participants from both training and validation sets, the serum levels for the 4 biomarkers we
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Current HIV vaccine strategies for preventing mucosal infect
2018-11-01
Current HIV fty720 strategies for preventing mucosal infection focus primarily on the induction of bnAbs or V1V2 IgG Abs with other antiviral functions. Vaccine efficacy trial outcomes require years of waiting but in vivo NHP and ex vivo human mucosal challenge models presented here can accelerate
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Protein tyrosine phosphatase B PTP B is
2018-11-01
Protein tyrosine phosphatase 1B (PTP1B) is a non-receptor tyrosine phosphatase that is widely expressed in the body, and negatively regulates leptin signaling by dephosphorylating Janus Activating Kinase 2 (JAK2) in the hypothalamus (Tsou and Bence, 2012; Myers et al., 2001; Zhang et al., 2015). Ani
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A second interesting conclusion that can be drawn
2018-11-01
A second interesting conclusion that can be drawn from our work concerns the paradoxical effect of PIO on Hq versus WT mice. PIO, a widely used hypoglycaemic drug, acted as predicted for a PPARγ ligand in WT mice, therefore decreasing glycaemia and weight, without significantly affecting motor perfo
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GSK1324726A br Patients and Methods In this retrospective co
2018-11-01
Patients and Methods In this retrospective cohort study we included 87 patients referred for analysis of recurrent RTI in the period 1992 until 2014. The clinical and immunological screening before starting ART comprised infection history and immune status investigation according to the immune st
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The complexity of identifying gene
2018-11-01
The complexity of identifying gene-environment interactions for Crohn\'s disease should be acknowledged. It is important to understand the design of the studies and the methodical implications of grouping multiple genetic variants into a single analysis. Helbig et al. were the first to use a case-on
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equol The decrease in Ab levels is undoubtedly caused by
2018-11-01
The decrease in Ab levels is undoubtedly caused by general deterioration of the immune response, which is well documented, not only in terms of decreased CD4+ T-cell counts but also in proliferative responses (Imami et al., 2013; Lewis et al., 2014). Here, we sought to quantify and characterize peri
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br Acknowledgments The data was
2018-11-01
Acknowledgments The data was collected with funding from the East Carolina University Department of Economics. Ju-Chin Huang collaborated with the author on the survey design. Value of the data Materials and methods Specifications table Data, experimental design, materials and methods
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