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In the present study recipient oestradiol
2021-11-04

In the present study, recipient oestradiol serum levels on the day of donor oocyte retrieval or warming were found to be significantly higher in the antagonist group and higher than 100 pg/ml in all cases. Serum oestradiol level has been reported to have no effect on endometrial receptiveness in ooc
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It is essential to maintain genome integrity and
2021-11-04

It is essential to maintain genome integrity and stability which is assaulted by oxidative stress. To perform this function, all human cells have well developed repair systems. Base excision repair (BER) system is the most effective pathway responsible to revert back lesions caused by oxidative stre
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br Acknowledgements br Introduction Aminoacyl tRNA synthetas
2021-11-04

Acknowledgements Introduction Aminoacyl-tRNA synthetases catalyze the formation of an ester bond between an amino Sildenafil mesylate and the 3′ end of a tRNA in a two-step reaction. First, the amino acid is activated and an enzyme-bound adenylate intermediate is formed. Then, the amino acid i
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Many studies support that Gli
2021-11-04

Many studies support that Gli transcription factors are not solely regulated by Hh/smo signaling but are also influenced by crosstalk with other pathways, such as RAS, PI3K/AKT, transforming growth factor-b/SMAD, PKC, or extracellular signal-regulated kinase pathways which are downstream and indepen
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br Concluding remarks In this small material of thirteen pit
2021-11-04

Concluding remarks In this small material of thirteen pituitary tumors of various kinds, we could not run statistical analysis. However, with a follow-up period of up to five years, we show that Disclosure Statement Acknowledgments Introduction Galanin is a 29/30-residue neuropeptide fo
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GSK-LSD1 hydrochloride At present many methods have been app
2021-11-04

At present, many methods have been applied for multiple detection. For example, GSK-LSD1 hydrochloride [[9], [10], [11]] is frequently used to detect multiple targets because of its exquisite sensitivity and specificity, but it is difficult to design experiments to test short-length oligonucleotide
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Guanethidine Sulfate mg The physicochemical properties of th
2021-11-04

The physicochemical properties of the prodrugs provided important clues for understanding a broad range of inhibitory activities in the cell assays (Table 2). Some physicochemical properties are useful in predicting drug absorption. Considering Lipinski’s rules and the polar surface area (PSA),l-ala
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PD PD L signaling is critical for
2021-11-04

PD-1/PD-L1 signaling is critical for the induction of exhausted CD8+ T Levodopa during the tumor immune response (Barber et al., 2006; Wherry et al., 2007; Wherry and Kurachi,2015; Pauken and Wherry, 2015), but the relationship between PD-1/PD-L1 signaling and Fas/FasL signaling in exhausted CD8+ T
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CTPB mg Much is known about FPPS structure and function with
2021-11-04

Much is known about FPPS structure and function, with over 120 FPPS crystal structures being currently available. This wealth of information is largely the consequence of human FPPS serving as a drug target for the treatment and/or prevention of pathologies such as osteoporosis, hypercalcemia and Pa
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The main consequence of glucose catabolism is the elevation
2021-11-04

The main consequence of glucose catabolism is the elevation of ATP concentration, which in turn suppresses the ATP sensitive potassium (KATP) channels gating function. The KATP channels are octamers composed of the tetrameric inward-rectifying potassium channels (with Kir6.1 and Kir6.2 subunits), th
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br Histamine H R The cloning of the
2021-11-04

Histamine H4R The cloning of the H3R (Lovenberg et al., 1999) provided a template for the search of other Hordenine sale receptors, and resulted in the most recent discovery of histamine H4R. This concluded with six independent groups that have reported the cloning of the H4R (Leurs et al., 2009
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A compound structurally similar to PF has been developed
2021-11-04

A Dihydroartemisinin sale structurally similar to PF-03654746 has been developed by Pfizer (PF-03654764), with a minor change in the substituent attached to the cyclobutanecarboxamide moiety (Wager et al., 2011). This compound, with the chemical name trans-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmet
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br Hepatitis C virus HCV infection is
2021-11-03

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease that can lead to cirrhosis and hepatocellular carcinoma. It is estimated that nearly 200 million individuals worldwide are currently infected with HCV and it is the leading cause of liver transplants. The current standard
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The translation of the HCV genomic RNA is initiated
2021-11-03

The translation of the HCV genomic RNA is initiated in a different manner, referred to as internal initiation: the 40S subunit directly forms a binary complex with the HCV genomic RNA via an internal RNA sequence called IRES, which is located in the 5′-UTR (Pestova et al., 1998, Tsukiyama-Kohara et
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Also in this work we investigated the correlated
2021-11-03

Also in this work, we investigated the correlated signaling pathways of GSK-3 inhibition in protecting bupivacaine-induced DRG neurotoxicity. Through western blot assay, we demonstrated that, SB216763 suppressed protein productions of p-GSK-3 α/β and Casp-3, but increased protein production of PKC,
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